Active aGeIng and Osteoporosis: The next challenge for smarT nanobiOmaterials and 3D technologies
Start Date: 01/01/2019,     End Date: 28/02/2023

GIOTTO is a EU-funded research and innovation project aimed to develop new medical devices to treat bone fractures, applying the most updated advances of “key enabling technologies”. The final aim is to offer specific solutions for the different types of osteoporotic fractures, stimulating bone regeneration while reducing bone loss.

Medical doctors, scientists and medical device producers from 14 organizations in 9 Countries around Europe work together to provide better treatment solutions with lower side effects to the increasing number of people suffering from painful and debilitating osteoporotic fractures. The new devices developments are based on cutting edge technologies in the fields of advanced manufacturing, nanotechnology, biotechnology and Internet of Things (IoT).

GIOTTO integrates different types of expertise to finally offer better treatment solutions for patients wellbeing, leveraging on technologies such as:

  • 3D-printing and the most updated technologies for bone scaffold manufacturing will be put in place together with nano-functionalisation for the smart release of active molecules and ions
  • Functionalised magnetic nanoparticles to allow controlled mechano-transduction
  • An Internet of Things platform will be developed to gather and collate measurable data inputs about device effectiveness and to provide decision support software as a service to improve the design, manufacture and clinical function of the proposed devices, ultimately managing the overall value chain
  • Safety and sustainability of the final solutions will guide the overall development since the beginning, though testing and the involvement of regulators

Principal Investigator

Prof. Chatzinikolaidou Maria
University Faculty Member


European Horizon 2020 framework